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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Bupropion hydrochloride (CAS 31677-93-7) is a small-molecule aminoketone that acts as a dual inhibitor of norepinephrine and dopamine reuptake with IC values of 6 5 0 6 M and 3 4 0 4 M respectively It is widely utilized in research for its established roles in modulating monoaminergic neurotransmission associated with depression and smoking cessation In cellular studies bupropion hydrochloride has been shown to decrease cell viability in SH-SY5Y neuroblastoma cells selectively induce endoplasmic reticulum stress and activate JNK pathways leading to caspase 3-dependent apoptosis Additionally it has been reported to downregulate tyrosine hydroxylase expression impacting dopamine biosynthesis
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More